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Estratetraenol (EST) Spray
Estratetraenol (EST) Spray
Brand: PheromoneXS
Product Code: EST-SPRAY
Availability: 19

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ESTratetraenol Pheromone Molecule

1, 3, 5(10), 16-ESTRATETRAEN-3-OL


1, 3, 5(10), 16-ESTRATETRAEN-3-OL (Estratetraenol) is a pheromone detectable in sweat and urine of human females and not detected at all in men. Rarely the scent has been associated with urine, but most people cannot smell it. Often times it is associated with sexual responses but also advantageous with calming, friendly and social aspects in both men and women.

Interestingly, Estratetreanol induces a complex effect on psychological states and brain function. It has the unique ability to influence mood response to a soothing calm state while simultaneously emotionally exciting. A study revealed Estratetreanol amplified dopamine receptors while also producing a morphine like response.

Predominantly a pheromone that is used by women its effects can warm the chilliest of attitudes of other women. In the presence of men the user will experience a discernible increase in attraction and closeness. They will want to be close to you and will initiate touching and cuddling. The conceptualized olfactory perception has been linked to an established pattern of gentleman like behavior of protector and lover.

On the female wearer you should expect a pronounced feminine appeal, increased attraction, engagement and sexual response. Some men in our community sourced research have indicated good results at very low dosages (2.5 mcg and below). However other men have reported increased aggression from other men.

A must have for every woman’s pheromone collection, while not so much for men. pheromoneXS recommends beginning at 12.5 mcg and higher for women with solid results indicative of sensual responses.


pheromoneXS ESTratetraenol is available in 10 ml or 30 ml bottles as multiple different concentrations which you can select from 12.5 mcg per spray up to 500 mcg per spray. Bottles come with Perfumers Alcohol (SD40B) as diluent time set with 10% Dipropylene Glycol (DPG). Whichever strength you select, you are sure to get the full potential of the pheromone molecule. Perfectly blended pheromone mixes are now in your control enabling you to effortlessly create your own pheromone masterpiece.

10 and 30 ml Spray Bottle with atomizer, custom designed to your concentration specifications, will produce approximately: 10ml = 80 sprays / 30ml = 240 sprays. Each bottle consists of ESTratetraenol pheromone molecule in solution of 90% Perfumers Alcohol (SD40B) with 10% Dipropylene Glycol (DPG) and are ready for immediate use.

Mcg Per Spray
Pheromone Content
Community Researcher Cost*
10ml at 12.5mcg/spray
1000 mcg (1 mg)
10ml at 25mcg/spray
2000 mcg (2 mg)
10ml at 50mcg/spray
4000 mcg (4 mg)
$45.97 $32.18
10ml at 75mcg/spray 
6000 mcg (6 mg)
$53.97 $37.78
10ml at 100mcg/spray
8000 mcg (8 mg)
10ml at 150mcg/spray
12000 mcg (12 mg)
10ml at 200mcg/spray
16000 mcg (16 mg)
30ml at 5mcg/spray
1000 mcg (1 mg)
30ml at 10mcg/spray
2000 mcg (2 mg)
30ml at 20mcg/spray
4000 mcg (4 mg)
30ml at 30mcg/spray
6000 mcg (6 mg)
30ml at 40mcg/spray
8000 mcg (8 mg)
30ml at 50mcg/spray
10000 mcg (10 mg)
30ml at 75mcg/spray
15000 mcg (15 mg)
30ml at 100mcg/spray
2000 mcg (20 mg)
30ml at 500mcg/spray
100000 mcg (100 mg)

*For approximation purposes only. Prices above may reflect our community sourced "Researcher" pricing discounts which can be as much as 30% off. For more information on how you can participate in our research and earn discounts yourself please visit our community at DiscoverXS.com

Each spray will contain the requested dosage with a possible differential of up to +/- 6%

Important Information
You agree that by ordering any Pheromone Molecules you are ordering a custom product made specifically for you. This process requires lab time and can add 3-5 business days (Monday through Friday excluding holidays) to your order processing times. pheromoneXS strives to exceed customer expectations, but you should expect possible delays when ordering these. Please consider this when ordering retail and custom products together.


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Facts Views Vis Obgyn. 2013;5(3):189-95.

Pheromones and their effect on women's mood and sexuality.

Verhaeghe J1, Gheysen R2, Enzlin P2.

PMID: 24753944


Pheromones are substances which are secreted to the outside by an individual and received by a second individual of the same species. Many examples exist in animals but their role in humans remains uncertain since adults have no functioning vomeronasal organ, which processes pheromone signals in animals. Yet pheromones can be detected by the olfactory system although humans under develop and underrate their smelling sense. Pheromones may be present in all bodily secretions but most attention has been geared toward axillary sweat which contains the odorous 16-androstenes. One of these steroidal compounds, androstadienone, is present at much higher concentrations in male sweat and can be detected by women, albeit with wide variation in sensitivity. Upper-lip application of a pharmacological dose of androstadienonein women results in improved mood and heightened focus - particularly to capture emotional information. A positive mood is known to facilitate women's sexual response, and -increased focus improves sexual satisfaction. Indeed, some studies showed a beneficial effect of androstadienone on sexual desire and arousal. However, these effects were dependent on the context of the experiment, for example, on the presence of a male attendant. Pheromones may also play a role in mate selection which is "disassortative" regarding the human leukocyte antigen (HLA)-genotype. Preliminary evidence suggests that exposure to androstadienone in women promotes attractiveness ratings of potential mates. In conclusion, some data indicate that 16-androstene pheromones, in particular androstadienone, play a beneficial role in women's mood, focus and sexual response, and perhaps also in mate selection.


PLoS One. 2013 Nov 7;8(11):e80234. doi: 10.1371/journal.pone.0080234. eCollection 2013.

Olfactory performance is predicted by individual sex-atypicality, but not sexual orientation.

Nováková L1, Varella Valentová J, Havlíček J.

PMID: 24244657


Many previous studies have reported robust sex differences in olfactory perception. However, both men and women can be expected to vary in the degree to which they exhibit olfactory performance considered typical of their own or the opposite sex. Sex-atypicality is often described in terms of childhood gender nonconformity, which, however, is not a perfect correlate of non-heterosexual orientation. Here we explored intrasexual variability in psychophysical olfactory performance in a sample of 156 individuals (83 non-heterosexual) and found the lowest odor identification scores in heterosexual men. However, when childhood gender nonconformity was entered in the model along with sexual orientation, better odor identification scores were exhibited by gender-nonconforming men, and greater olfactory sensitivity by gender-conforming women, irrespective of their sexual orientation. Thus, sex-atypicality, but not sexual orientation predicts olfactory performance, and we propose that this might not be limited to olfaction, but represent a more general phenomenon.


Front Endocrinol (Lausanne). 2013 Oct 28;4:159. doi: 10.3389/fendo.2013.00159. eCollection 2013.

Changes in Men's Salivary Testosterone and Cortisol Levels, and in Sexual Desire after Smelling Female Axillary and Vulvar Scents.

Cerda-Molina AL1, Hernández-López L, de la O CE, Chavira-Ramírez R, Mondragón-Ceballos R.

PMID: 24194730


Several studies have shown that a woman's vaginal or axillary odors convey information on her attractivity. Yet, whether such scents induce psychoneuroendocrinological changes in perceivers is still controversial. We studied if smelling axillary and vulvar odors collected in the periovulatory and late luteal phases of young women modify salivary testosterone and cortisol levels, as well as sexual desire in men. Forty-five women and 115 men, all of them college students and unacquainted with each other, participated in the study. Female odors were collected on pads affixed to the axilla and on panty protectors both worn the entire night before experiments. Men provided five saliva samples, a basal one before the smelling procedure, and four more 15, 30, 60, and 75 min after exposure to odors. Immediately after smelling the odor source, men answered a questionnaire rating hedonic qualities of scents, and after providing the last saliva sample they answered questionnaire on sexual desire. We found that periovulatory axillary and vulvar odors increased testosterone and cortisol levels, with vulvar scents producing a more prolonged effect. Luteal axilla odors decreased testosterone and cortisol levels, while luteal vulva odors increased cortisol. Periovulatory axilla and vulva scents accounted for a general increase of interest in sex. These odors were also rated as more pleasant and familiar, while luteal vulvar odors were perceived as intense and unpleasant.



Horm Behav. 2013 May;63(5):723-41. doi: 10.1016/j.yhbeh.2013.03.011. Epub 2013 Mar 29.

Chemosignals, hormones and mammalian reproduction.

Petrulis A.

PMID: 23545474


Many mammalian species use chemosignals to coordinate reproduction by altering the physiology and behavior of both sexes. Chemosignals prime reproductive physiology so that individuals become sexually mature and active at times when mating is most probable and suppress it when it is not. Once in reproductive condition, odors produced and deposited by both males and females are used to find and select individuals for mating. The production, dissemination and appropriate responses to these cues are modulated heavily by organizational and activational effects of gonadal sex steroids and thereby intrinsically link chemical communication to the broader reproductive context. Many compounds have been identified as "pheromones" but very few have met the expectations of that term: a unitary, species-typical substance that is both necessary and sufficient for an experience-independent behavioral or physiological response. In contrast, most responses to chemosignals are dependent or heavily modulated by experience, either in adulthood or during development. Mechanistically, chemosignals are perceived by both main and accessory (vomeronasal) olfactory systems with the importance of each system tied strongly to the nature of the stimulus rather than to the response. In the central nervous system, the vast majority of responses to chemosignals are mediated by cortical and medial amygdala connections with hypothalamic and other forebrain structures. Despite the importance of chemosignals in mammals, many details of chemical communication differ even among closely related species and defy clear categorization. Although generating much research and public interest, strong evidence for the existence of a robust chemical communication among humans is lacking.

Copyright © 2013 Elsevier Inc. All rights reserved.

Pheromone Molecules
Molecular Name 1, 3, 5(10), 16-ESTRATETRAEN-3-OL
Documents pheromoneXS is striving to provide our valued clients with data sheets on every named pheromone molecule we sell, so you can buy with confidence. We are continually having each molecule assayed by independent third party laboratories like Sigma-Aldrich, Steraloids and Intertek. Accessibility to this data is an ongoing project that we are committed to, however not all components have been completed yet. We appreciate your patience and understanding.
Synonyms Estra-1,3,5(10),16-tetraen-3-ol, ESTRATETRAENOL, EST
CAS Number 1150-90-9
Empirical Formula (Hill Notation) C18 H22 O
Molecular Weight 254.37
Melting Point 135-137˚C
Application 1, 3, 5(10), 16-ESTRATETRAEN-3-OL (Estratetreanol) produced by females is a pheromone by-product of estradiol, an estrogen sex hormone, but shows no estrogenic effects. This pheromone is predominantly used by women to induce a calming state in other women and men Produces an allure of femininity and sensual appeal.

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