ESTratetraenol Pheromone Molecule
1, 3, 5(10), 16-ESTRATETRAEN-3-OL
1, 3, 5(10), 16-ESTRATETRAEN-3-OL (Estratetraenol) is a pheromone detectable in sweat and urine of human females and not detected at all in men. Rarely the scent has been associated with urine, but most people cannot smell it. Often times it is associated with sexual responses but also advantageous with calming, friendly and social aspects in both men and women.
Interestingly, Estratetraenol induces a complex effect on psychological states and brain function. It has the unique ability to influence mood response to a soothing calm state while simultaneously emotionally exciting. A study revealed Estratetraenol amplified dopamine receptors while also producing a morphine like response.
Predominantly a pheromone that is used by women its effects can warm the chilliest of attitudes of other women. In the presence of men the user will experience a discernible increase in attraction and closeness. They will want to be close to you and will initiate touching and cuddling. The conceptualized olfactory perception has been linked to an established pattern of gentleman like behavior of protector and lover.
On the female wearer you should expect a pronounced feminine appeal, increased attraction, engagement and sexual response. Some men in our community sourced research have indicated good results at very low dosages (2.5 mcg and below). However other men have reported increased aggression from other men.
A must have for every woman’s pheromone collection, while not so much for men. pheromoneXS recommends beginning at 12.5 mcg and higher for women with solid results indicative of sensual responses.
pheromoneXS Estratetraenol is available in 10ml bottle as multiple different concentrations which you can select from 5 mcg per drop up to 100 mcg per drop. Bottles come with Dipropylene Glycol (DPG) as diluent. Whichever strength you select, you are sure to get the full potential of the pheromone molecule. Perfectly blended pheromone mixes are now in your control enabling you to effortlessly create your own pheromone masterpiece.
10ml Amber Bottle with attached dropper custom designed to your concentration specifications, will produce approximately: 10ml = 300 drops. Each bottle consists of Estratetraenol pheromone molecule in solution of Dipropylene Glycol (DPG) and are ready for immediate use.
Each drop will contain the requested dosage with a possible differential of up to +/- 6%
You agree that by ordering any Pheromone Molecules you are ordering a custom product made specifically for you. This process requires lab time and can add 3-5 business days (Monday through Friday excluding holidays) to your order processing times. pheromoneXS strives to exceed customer expectations, but you should expect possible delays when ordering these. Please consider this when ordering retail and custom products together.
All Oil Bottles are shipped with a polycone cap to prevent leakage.
We value our clients feedback, which is why we offer 2 different types of dropper caps.
Both methods have their proponents and you must choose which one you’d like to be included, on the side, with your order. It’s a good rule of thumb, to only bring the quantity you plan to use when traveling. If you do plan to travel with the oil bottle please use the included polycone cap to prevent any leakage. XS is not responsible for any leakage that might occur regardless of what cap you utilize.
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Facts Views Vis Obgyn. 2013;5(3):189-95.
Pheromones and their effect on women's mood and sexuality.
Verhaeghe J1, Gheysen R2, Enzlin P2.
Pheromones are substances which are secreted to the outside by an individual and received by a second individual of the same species. Many examples exist in animals but their role in humans remains uncertain since adults have no functioning vomeronasal organ, which processes pheromone signals in animals. Yet pheromones can be detected by the olfactory system although humans under develop and underrate their smelling sense. Pheromones may be present in all bodily secretions but most attention has been geared toward axillary sweat which contains the odorous 16-androstenes. One of these steroidal compounds, androstadienone, is present at much higher concentrations in male sweat and can be detected by women, albeit with wide variation in sensitivity. Upper-lip application of a pharmacological dose of androstadienonein women results in improved mood and heightened focus - particularly to capture emotional information. A positive mood is known to facilitate women's sexual response, and -increased focus improves sexual satisfaction. Indeed, some studies showed a beneficial effect of androstadienone on sexual desire and arousal. However, these effects were dependent on the context of the experiment, for example, on the presence of a male attendant. Pheromones may also play a role in mate selection which is "disassortative" regarding the human leukocyte antigen (HLA)-genotype. Preliminary evidence suggests that exposure to androstadienone in women promotes attractiveness ratings of potential mates. In conclusion, some data indicate that 16-androstene pheromones, in particular androstadienone, play a beneficial role in women's mood, focus and sexual response, and perhaps also in mate selection.
PLoS One. 2013 Nov 7;8(11):e80234. doi: 10.1371/journal.pone.0080234. eCollection 2013.
Olfactory performance is predicted by individual sex-atypicality, but not sexual orientation.
Nováková L1, Varella Valentová J, Havlíček J.
Many previous studies have reported robust sex differences in olfactory perception. However, both men and women can be expected to vary in the degree to which they exhibit olfactory performance considered typical of their own or the opposite sex. Sex-atypicality is often described in terms of childhood gender nonconformity, which, however, is not a perfect correlate of non-heterosexual orientation. Here we explored intrasexual variability in psychophysical olfactory performance in a sample of 156 individuals (83 non-heterosexual) and found the lowest odor identification scores in heterosexual men. However, when childhood gender nonconformity was entered in the model along with sexual orientation, better odor identification scores were exhibited by gender-nonconforming men, and greater olfactory sensitivity by gender-conforming women, irrespective of their sexual orientation. Thus, sex-atypicality, but not sexual orientation predicts olfactory performance, and we propose that this might not be limited to olfaction, but represent a more general phenomenon.
Front Endocrinol (Lausanne). 2013 Oct 28;4:159. doi: 10.3389/fendo.2013.00159. eCollection 2013.
Changes in Men's Salivary Testosterone and Cortisol Levels, and in Sexual Desire after Smelling Female Axillary and Vulvar Scents.
Cerda-Molina AL1, Hernández-López L, de la O CE, Chavira-Ramírez R, Mondragón-Ceballos R.
Several studies have shown that a woman's vaginal or axillary odors convey information on her attractivity. Yet, whether such scents induce psychoneuroendocrinological changes in perceivers is still controversial. We studied if smelling axillary and vulvar odors collected in the periovulatory and late luteal phases of young women modify salivary testosterone and cortisol levels, as well as sexual desire in men. Forty-five women and 115 men, all of them college students and unacquainted with each other, participated in the study. Female odors were collected on pads affixed to the axilla and on panty protectors both worn the entire night before experiments. Men provided five saliva samples, a basal one before the smelling procedure, and four more 15, 30, 60, and 75 min after exposure to odors. Immediately after smelling the odor source, men answered a questionnaire rating hedonic qualities of scents, and after providing the last saliva sample they answered questionnaire on sexual desire. We found that periovulatory axillary and vulvar odors increased testosterone and cortisol levels, with vulvar scents producing a more prolonged effect. Luteal axilla odors decreased testosterone and cortisol levels, while luteal vulva odors increased cortisol. Periovulatory axilla and vulva scents accounted for a general increase of interest in sex. These odors were also rated as more pleasant and familiar, while luteal vulvar odors were perceived as intense and unpleasant.
Horm Behav. 2013 May;63(5):723-41. doi: 10.1016/j.yhbeh.2013.03.011. Epub 2013 Mar 29.
Chemosignals, hormones and mammalian reproduction.
Many mammalian species use chemosignals to coordinate reproduction by altering the physiology and behavior of both sexes. Chemosignals prime reproductive physiology so that individuals become sexually mature and active at times when mating is most probable and suppress it when it is not. Once in reproductive condition, odors produced and deposited by both males and females are used to find and select individuals for mating. The production, dissemination and appropriate responses to these cues are modulated heavily by organizational and activational effects of gonadal sex steroids and thereby intrinsically link chemical communication to the broader reproductive context. Many compounds have been identified as "pheromones" but very few have met the expectations of that term: a unitary, species-typical substance that is both necessary and sufficient for an experience-independent behavioral or physiological response. In contrast, most responses to chemosignals are dependent or heavily modulated by experience, either in adulthood or during development. Mechanistically, chemosignals are perceived by both main and accessory (vomeronasal) olfactory systems with the importance of each system tied strongly to the nature of the stimulus rather than to the response. In the central nervous system, the vast majority of responses to chemosignals are mediated by cortical and medial amygdala connections with hypothalamic and other forebrain structures. Despite the importance of chemosignals in mammals, many details of chemical communication differ even among closely related species and defy clear categorization. Although generating much research and public interest, strong evidence for the existence of a robust chemical communication among humans is lacking.
Copyright © 2013 Elsevier Inc. All rights reserved.
|Molecular Name||1, 3, 5(10), 16-ESTRATETRAEN-3-OL|
|Documents||pheromoneXS is striving to provide our valued clients with data sheets on every named pheromone molecule we sell, so you can buy with confidence. We are continually having each molecule assayed by independent third party laboratories like Sigma-Aldrich, Steraloids and Intertek. Accessibility to this data is an ongoing project that we are committed to, however not all components have been completed yet. We appreciate your patience and understanding.|
|Synonyms||ESTratetraenol, EST, 1, 3, 5(10), 16-ESTRATETRAEN-3-OL|
|Empirical Formula (Hill Notation)||C18 H22 O|
|Application||1, 3, 5(10), 16-ESTRATETRAEN-3-OL (Estratetraenol) produced by females is a pheromone by-product of estradiol, an estrogen sex hormone, but shows no estrogenic effects. This pheromone is predominantly used by women to induce a calming state in other women and men Produces an allure of femininity and sensual appeal.|